cell death-inducing p53-target protein 1; cell death involved p53-target; cell death-inducing protein; LITAF-like protein; lipopolysaccharide-induced tumor necrosis factor-alpha-like protein; transmembrane protein I1 (CDIP1 C16orf5 CDIP LITAFL)

Function

• p53 apoptosis effector
• regulates TNF-alpha-mediated apoptosis (p53-dependent)

Structure

belongs to the CDIP1/LITAF family

Alternative splicing

• named isoforms=3
• competing acceptor splice site

Expression

• highly expressed in brain
• expressed at lower level in heart, skeletal muscle, kidney, pancreas & liver
• weakly or not expressed in placenta & lung
• up-regulated by p53

More general terms

• other protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=29965
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:29965
• OMIM: https://mirror.omim.org/entry/610503
• UniProt: http://www.uniprot.org/uniprot/Q9H305.html