mitochondrial dynamic protein MID51; mitochondrial dynamic protein of 51 kD; mitochondrial elongation factor 1; Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like (MIEF1, MID51, SMCR7L)
Jump to navigation
Jump to search
Function
- mitochondrial outer membrane protein
- regulates mitochondrial fission
- promotes recruitment & association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 & MFF proteins
- interacts with DNM1L
Structure
- homodimer
- belongs to the SMCR7 family
Compartment
- mitochondrial outer membrane; single-pass membrane protein
Expression
- relatively high expression in heart, skeletal muscle, pancreas & kidney