obinutuzumab (Gazyva)
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Indications
- treatment-naive patients with chronic lymphocytic leukemia
- for use with chlorambucil
- 1st line treatment of follicular lymphoma[2]
Adverse effects
- infusion-related reactions
- associated with severe COVID-19 infection[3]
- boxed warning
- potential risks for hepatitis B virus reactivation & progressive multifocal leukoencephalopathy
More general terms
References
- ↑ FDA News Release: Nov. 1, 2013 FDA approves Gazyva for chronic lymphocytic leukemia http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm373209.htm
- ↑ 2.0 2.1 2.2 Marcus R, Davies A, Ando K et al Obinutuzumab for the First-Line Treatment of Follicular Lymphoma. N Engl J Med 2017; 377:1331-1344. October 5, 2017 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28976863 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1614598
- ↑ 3.0 3.1 Ingram I Anti-CD20 Drugs Tied to Severe COVID in Cancer Patients - Plus: Active chemo treatment may not be a COVID risk factor. MedPage Today February 5, 2021 https://www.medpagetoday.com/hematologyoncology/lymphoma/91092