drug adverse effects of lipophilic statins
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Adverse effects
- discontinuation of lipophilic statin* increases risk of Parkinson's disease[1]
- acute memory impairment within 30 days (RR=4.4, all antihyperlipidemic agents)[2]
* lipophilic statins cross the blood brain barrier
More general terms
References
- ↑ 1.0 1.1 Physician's First Watch, July 25, 2013 David G. Fairchild, MD, MPH, Editor-in-Chief Massachusetts Medical Society http://www.jwatch.org
Lee Y-C et al. Discontinuation of statin therapy associates with Parkinson disease: A population <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23884037 <Internet> http://neurology.org/content/early/2013/07/24/WNL.0b013e31829d873c - ↑ 2.0 2.1 Strom BL et al Statin Therapy and Risk of Acute Memory Impairment. JAMA Intern Med. Published online June 08, 2015 http://archinte.jamanetwork.com/article.aspx?articleID=2301148