pomalidomide (Pomalyst)

Indications

• treatment of multiple myeloma after progression of disease with lenalidomide & bortezomib treatment

Contraindications

• pregnancy

Adverse effects

• neutropenia, anemia, thrombocytopenia
• venous thromboembolism
• fatigue, weakness
• constipation, diarrhea
• upper respiratory tract infections
• back pain
• fever

Mechanism of action

• modulates immune system
• the other 2 drugs in this class, lenalidomide & thalidomide, are also angiogenesis inhibitors

More general terms

• antineoplastic immunomodulator

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=134780