fluticasone/salmeterol (Advair/Seretide Diskus, Wixela, AirDuo Respiclick)

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Introduction

Combination inhaler for asthma.

Generic Advair Diskus FDA-approved Jan 2019[8]

Indications

Contraindications

Dosage

2 puffs BID

Dry powder inhaler:

Storage

good for one month after opening

Adverse effects

Clinical trials

More general terms

Components

References

  1. Prescriber's Letter 8(2):supplement 2001
  2. Prescriber's Letter 8(4):22 2001
  3. Lyseng-Williamson KA & Plosker GL, Pharmacoeconomics 21:951, 2003 PMID: https://www.ncbi.nlm.nih.gov/pubmed/12959627
  4. 4.0 4.1 FDA Medwatch http://www.fda.gov/medwatch/safety/2005/safety05.htm#LABA
  5. Prescriber's Letter 16(9): 2009 COMMENTARY: Shortened Expiration Dating of Some Inhalation Products PATIENT HANDOUT: Tips for Correct Use of Inhalers Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=250903&pb=PRL (subscription needed) http://www.prescribersletter.com
  6. 6.0 6.1 Deprecated Reference
  7. 7.0 7.1 Stempel DA et al Serious Asthma Events with Fluticasone plus Salmeterol versus Fluticasone Alone. N Engl J Med. March 6, 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26949137 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1511049
    Martinez FD Safety of Fluticasone plus Salmeterol in Asthma - Reassuring Data, but No Final Answer. N Engl J Med. March 6, 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26946980 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMe1601040
  8. 8.0 8.1 FDA News Release. Jan 20, 2019 FDA approves first generic Advair Diskus https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm630151.htm

Database