difenoxin

Uses

• used in combination with atropine for treatment of diarrhea

Mechanism of action

• active metabolite of the anti-diarrhea drug diphenoxylate
• works primarily on opioid receptors in the intestines
• crosses blood brain barrier, thus has some central action on opioid receptors

More general terms

• opioid receptor agonist (narcotic)
• anti-motility agent; antiperistaltic agent

Component of

• atropine/difenoxin (Motofen)