aluminum hydroxide/magnesium hydroxide (Maalox, Mylanta)

Indications

• symptomatic treatment of dyspepsia, GERD & peptic ulcer disease (PUD)

Contraindications

pregnancy-category +, ? (1st trimester)

safety in lactation ?

Dosage

• 1 tab or 15-30 mL PO PRN.

Pharmacokinetics

elimination: kidney

Adverse effects

• constipation
• decrease in GI motility
• long term use in patients with renal failure may result in aluminum toxicity
• diarrhea may occur with magnesium-containing products
• long-term use of magnesium-containing products in patients with renal failure may lead to hypermagnesemia

Mechanism of action

• neutralizes gastric acid

Notes

• Maalox Plus & Mylanta II have added simethicone

More general terms

• pharmacologic combination

More specific terms

• aluminum hydroxide/magnesium hydroxide/simethicone (Mylanta II, Maalox Plus)

Component of

• calcium carbonate/maalox/simethicone
• Maalox/Mylanta/viscous lidocaine/Donnatal (GI cocktail, 'Green Goddess')

Components

• aluminum hydroxide (Alternagel, Amphojel, Alu-Cap, Dialume, AlH3OH)
• magnesium hydroxide (Milk of Magnesia)