Ranson criteria
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Introduction
Ranson criteria provides prognostic information for patients with pancreatitis. Increased morbidity & mortality are associated with the following criteria:
Upon admission to hospital:
- age > 55 years (> 70 for gallstone pancreatitis)
- WBC > 16,000/mm3 (> 18,000 for gallstone pancreatitis)
- glucose > 200 mg/dL (> 220 for gallstone pancreatitis)
- serum LDH > 350 IU/L (> 400 for gallstone pancreatitis) [for reference interval of 90-280 IU/L]
- AST > 250 IU/L
After 48 hours:
- hematocrit* drop of > 10%
- rise in serum urea nitrogen* > 5 mg/dL (> 2 for gallstone pancreatitis)
- arterial pO2 < 60 mm Hg (not a criterium for gallstone pancreatitis)
- base deficit > 4 meq/L (> 5 meq/L for gallstone pancreatitis)
- serum Ca+2 < 8.0 mg/dL
- estimated fluid sequestration > 6 L (> 4 L for gallstone pancreatitis)
* see notes
Notes
- serial serum urea nitrogen provides the most reliable routine laboratory test to predict mortality[4]
- changes in blood hemoglobin do not correlate with disease severity[4]
More general terms
Additional terms
References
- ↑ Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 361
- ↑ Ranson et al Sur Gynecol Obstet 139:69 1974
- ↑ Ranson Am J Gastroenterol 77:633 1982
- ↑ 4.0 4.1 4.2 Medical Knowledge Self Assessment Program (MKSAP) 16 American College of Physicians, Philadelphia 2012