F-box only protein 44; F-box/G-domain protein 3; F-box protein FBX30 (FBXO44, FBG3, FBX30, FBX44, FBX6A, FBXO6A)

Function

• substrate-recognition component of the SCF complex (putative) 0 directly interacts with SKP1A & CUL1 (putative)

Structure

• contains 1 F-box domain
• contains 1 FBA (F-box associated) domain

Alternative splicing

named isoforms=2

Expression

• abundantly expressed in brain & kidney
• expressed at lower levels in heart, spleen & liver

More general terms

• F-box only protein

Component of

• SCF-type E3 ligase complex

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=93611
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:93611
• OMIM: https://mirror.omim.org/entry/609111
• UniProt: http://www.uniprot.org/uniprot/Q9H4M3.html