zinc finger BED domain-containing protein 6 (ZBED6)

Function

• transcriptional repressor which binds to the consensus sequence 5'-GCTCGC-3' & represses transcription of IGF2
• may also regulate expression of other target genes containing this consensus binding site (putative)

Structure

• contains 2 BED-type Zn+2 fingers

Compartment

• nucleus, nucleolus (putative)
• located predominantly in the nucleolus butalso dispersed throughout the nucleus (putative)

Notes

• encoded by an exapted DNA transposon located in an intron of the ZC3H11A gene

More general terms

• nuclear protein
• zinc finger protein

Database

• UniProt: http://www.uniprot.org/uniprot/P86452.html