interleukin-22 receptor (IL22R, IL19R, IL24R)

Function

• enables IL22 signaling via JAK/STAT pathways
• IL22 also induces activation of MAPK1/MAPK3 & Akt kinases pathways

Structure

• formed by IL22RA1 & IL10RB

Notes

• IL22RA2 serves as a secreted IL22 receptor decoy

More general terms

• interleukin receptor
• multisubunit protein