platelet factor 4 variant; C-X-C motif chemokine 4 variant; CXCL4L1; PF4alt; PF4var1 (PF4V1, CXCL4V1, SCYB4V1)

Function

• inhibitor of angiogenesis
• inhibitor of endothelial cell chemotaxis (in vitro)
• the N-terminal processed forms of platelet factor 4 variant seems to be produced by proteolytic cleavage
• the most abundant form is platelet factor 4 variant(5-74)

Structure

• belongs to the intercrine alpha (chemokine CxC) family

Compartment

secreted

Notes

• unclear whether this is a different protein than platelet factor 4

More general terms

• platelet factor 4

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5197
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5197
• OMIM: https://mirror.omim.org/entry/173461
• UniProt: http://www.uniprot.org/uniprot/P10720.html