keratin, type 2 cytoskeletal 6C; cytokeratin-6C; CK 6C; K6c keratin; cytokeratin-6E; CK 6E; keratin K6h (KRT6C, KRT6E)

Function

• KRT6 isomers associate with KRT16 &/or KRT17

Structure

• heterodimer of a type 1 & a type 2 keratin
• belongs to the intermediate filament family

Expression

• constitutively expressed in distinct types of epithelia including those in oral mucosa, esophagus, papillae of tongue & hair follicle outer root sheath

Notes

• there are at least six isoforms of human type 2 keratin-6

More general terms

• cytokeratin 6 (K6)

Database

• UniProt: http://www.uniprot.org/uniprot/P48668.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=286887
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:286887
• OMIM: https://mirror.omim.org/entry/612315