galectin-16 (LGALS16)

Function

• binds lactose with high affinity. strong inducer of T-cell apoptosis

Structure

contains 1 galectin domain

Expression

• predominantly & highly expressed in placenta where it is localized mainly in the syncytiotrophoblast & in the endothelia of fetal vessels
• also detected in theamnion & chorionic trophoblasts in fetal membranes

More general terms

• uncharacterized protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=148003
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:148003
• UniProt: http://www.uniprot.org/uniprot/A8MUM7.html