ataxin-1-like; brother of ataxin-1 (ATXN1L, BOAT)

Function

• can supress the cytotoxicity of ATXN1 in spinocerebellar ataxia type 1 (SCA1) (putative)
• interacts with CIC (putative)
• interacts (via AXH domain) with NCOR2
• interacts with ATXN1

Structure

• homodimer
• belongs to the ATXN1 family
• contains 1 AXH domain

Compartment

• nucleus
• cell projection, dendrite
• nuclear foci
• colocalizes with NCOR2 & HDAC3
• distributed beyond the nucleus into the cell body & dendrites in Purkinje cells & in inferior olive cells

Expression

expressed in cerebellum & cerebral cortex

More general terms

• nuclear protein

Database

• UniProt: http://www.uniprot.org/uniprot/P0C7T5.html