Tau/Abeta42 in CSF; amyloid-tau neurodegeneration (ATN) profile
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Indications
- in conjunction with phosphorylated tau in CSF (phospho-Thr(181) tau), may be useful for predicting likelihood of MCI progressing to Alzheimer's disease[1][2]
Differential diagnosis
More general terms
More specific terms
Additional terms
- amyloid-beta peptide 42 in CSF
- cerebrospinal fluid
- microtubule-associated protein tau (neurofibrillary tangle protein, paired helical filament-tau, PHF-tau, MAPT, MTBT1)
- microtubule-associated protein tau in serum/plasma
Components
References
- ↑ 1.0 1.1 Mattsson N et al. CSF Biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA 2009 Jul 22/29; 302:385. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19622817
Petersen RC and Trojanowski JQ. Use of Alzheimer disease biomarkers: Potentially yes for clinical trials but not yet for clinical practice. JAMA 2009 Jul 22/29; 302:436. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19622825 - ↑ 2.0 2.1 Soldan A, Pettigrew C, Fagan AM et al. ATN profiles among cognitively normal individuals and longitudinal cognitive outcomes. Neurology 2019 Apr 2; 92:e1567 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30842300 https://n.neurology.org/content/92/14/e1567
- ↑ Lab Tests Online http://www.labtestsonline.org/understanding/analytes/tau/faq.html
Tau/Abeta42 Lab Tests Online: http://www.labtestsonline.org/understanding/analytes/tau/glance.html