cone-rod dystrophy (CORD)

Introduction

inherited retinal dystrophies belonging to the group of pigmentary retinopathies

Pathology

• retinal pigment deposits visible on fundus examination, predominantly in the macular region
• initial loss of cone photoreceptors followed by rod degeneration

Genetics

• X-linked cone-rod dystrophy
• dominant cone-rod dystrophy

Clinical manifestations

• decreased visual acuity & sensitivity in the central visual field, followed by loss of peripheral vision
• severe loss of vision occurs earlier than in retinitis pigmentosa

More general terms

• retinal disease
• genetic disease of the eye

More specific terms

• cone-rod dystrophy type 10 (CORD10)
• cone-rod dystrophy type 12
• cone-rod dystrophy type 2
• cone-rod dystrophy type 3
• cone-rod dystrophy type 5
• cone-rod dystrophy type 7 (CORD7)
• dominant cone-rod dystrophy
• Newfoundland rod-cone dystrophy (NFRCD)
• X-linked cone-rod dystrophy