renal tubular dysgenesis

Pathology

• severe disorder of renal tubular development
• pulmonary hypoplasia from early-onset oligohydramnios (Potter phenotype)

Genetics

• autosomal recessive
• associated with defects in AGTR1
• associated with defects in renin

Clinical manifestations

• persistent fetal anuria
• perinatal death

More general terms

• congenital anomaly (birth defect)
• genetic disease of the kidney
• renal tubular disease

Database

• OMIM: https://mirror.omim.org/entry/267430