methionine

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Introduction

One of the essential sulfur amino acids. Either cysteine or methionine is nutritionally required*. Either may be synthesized from the other, but without one, the other cannot be synthesized.*

* Homocysteine would also suffice.

Methionine is formed from methylation of homocysteine catalyzed by methionine synthase. It may also be formed from homocysteine & betaine in a reaction catalyzed by betaine homocysteine methyl- transferase.

Methionine combines with ATP to yield S-adenosylmethionine (SAM) in a reaction catalyzed by methionine adenosyltransferase.

Laboratory

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References

  1. Stryer Biochemistry WH Freeman & Co, New York, 1988 pg 582

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