pemphigus
Jump to navigation
Jump to search
Etiology
- pemphigus foliaceus (mildest form)
- pemphigus vulgaris
- paraneoplastic pemphigus
- drug-induced
- thiols (D-penicillamine, captopril, gold salts, pyritinol)
- amoxicillin, ampicillin, cephalosporin
- rifampin
Epidemiology
rare
Clinical manifestations
- vesiculobullous lesions
- flaccid fragile blisters that progress to large, weeping denuded areas
- oropharyngeal erosions are common
- chronic disorder
- see specific types
Laboratory
- skin biopsy
- direct immunofluorescence testing of perilesional skin
- histopathology of lesional skin
- see ARUP consult[2]
More general terms
More specific terms
- benign familial pemphigus (Hailey-Hailey disease)
- IgA pemphigus
- paraneoplastic pemphigus
- pemphigus foliaceus
- pemphigus vegetans
- pemphigus vulgaris
References
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 15, 16, 17. American College of Physicians, Philadelphia 2009, 2012, 2015
- ↑ 2.0 2.1 ARUP Consult: Pemphigus The Physician's Guide to Laboratory Test Selection & Interpretation https://arupconsult.com/content/pemphigus
- ↑ Kridin K. Pemphigus group: overview, epidemiology, mortality, and comorbidities. Immunol Res. 2018;66:255-70. PMID: https://www.ncbi.nlm.nih.gov/pubmed/29479654