hepatitis G virus; GB virus C (GBV-C)

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Originally isolated from hepatitis patients & called hepatitis G virus.



does NOT cause hepatitis or any other known human disease

GBV-C appears to inhibit pathogenesis of HIV[3]


More general terms

Additional terms


  1. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 1066
  2. Journal Watch 21(20):159, 2001 Xiang et al NEJM 345:707, 2001 Tillmann et al NEJM 345:715, 2001 Stoso & Wolinsky, NEJM 345:761, 2001
  3. 3.0 3.1 3.2 Ramezani A et al Frequency of hepatitis G virus infection among HIV positive subjects with parenteral and sexual exposure. J Gastrointestin Liver Dis. 2008 Sep;17(3):269-72. PMID: https://www.ncbi.nlm.nih.gov/pubmed/18836618
    Shankar EM et al GB virus infection: a silent anti-HIV panacea within? Trans R Soc Trop Med Hyg. 2008 May 28. [Epub ahead of print] PMID: https://www.ncbi.nlm.nih.gov/pubmed/18513775
    Jung S, HIV entry inhibition by the envelope 2 glycoprotein of GB virus C. AIDS. 2007 Mar 12;21(5):645-7. PMID: https://www.ncbi.nlm.nih.gov/pubmed/17314528
  4. Reshetnyak VI, Karlovich TI, Ilchenko LU. Hepatitis G virus. World J Gastroenterol. 2008 Aug 14;14(30):4725-34. PMID: https://www.ncbi.nlm.nih.gov/pubmed/18720531