nucleolar organizing region
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Introduction
Regions where the nucleus reforms after mitosis. Clusters of ribosomal RNA genes may be found. Antigens recognized by autoantibodies in scleroderma may be found within this region including Scl-70, fibrillarin, RNA polymerase I & NOR-90.
More general terms
Additional terms
- nucleolar transcription factor 1; autoantigen NOR-90; upstream-binding factor 1; UBF-1 (UBTF, UBF, UBF1)
- nucleolus
- scleroderma (diffuse cutaneous systemic sclerosis)
Component of
References
- ↑ Clinical Diagnosis & Management by Laboratory Methods, 19th edition, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1996, pg 1019