ribosomal RNA gene (rRNA gene)
Jump to navigation
Jump to search
Function
- tempate for rRNA transcribed by RNA polymerase 1
- present in tandem repeats
- transcription of these genes yields a large 45S pre-rRNA, which is then processed to yield the 28S, 18S, and 5.8S rRNAs
- the promoter of ribosomal RNA genes spans about 150 base pairs just upstream of the transcription initiation site
- promoter sequences are recognized by 2 transcription factors, UBF (upstream binding factor) & SL1 (selectivity factor 1), which bind cooperatively to the promoter & then recruit RNA polymerase 1 to form an initiation complex
More general terms
More specific terms
References
- ↑ from the NCBI bookshelf The Cell - A Molecular Approach. 2nd ed. Cooper, Geoffrey M. Sunderland (MA): Sinauer Associates, Inc; c2000 http://www.ncbi.nlm.nih.gov/books/bv.fcgi?highlight=RNA%20polymerase&rid=cooper.section.980#