antiarrhythmic agent, Group III
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Indications
- atrial fibrillation/atrial flutter
- ventricular arrhythmias
- chemical cardioversion[4]
- cardiac arrest[4]
Mechanism of action
- prolongs action potential duration
- class III antiarrhythmic agents block K+ channel
- thus class III agents prolong the action potential duration, repolarization, ventricular refractoriness & the QT interval
- to a lesser extent, class III agents diminish conduction velocity
More general terms
More specific terms
References
- ↑ Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 159
- ↑ Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 125
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 15, 16. American College of Physicians, Philadelphia 2009, 2012
- ↑ 4.0 4.1 4.2 Deprecated Reference