adenosylcobalamin; cobamamide (vitamin B12)

Introduction

Adenosylcobalamin the cofactor of methylmalonyl CoA mutase, an enzyme involved in the metabolism of propionate formed from catabolism of odd chain fatty acids, cholesterol & the amino acids methionine, valine & isoleucine (via propionyl CoA).

See methylmalonyl CoA mutase.

Methylmalonic aciduria type A protein may be involved in the t ransport of cobalamin into mitochondria for the final steps of adenosylcobalamin synthesis.

More general terms

• vitamin B12; cobalamin

Additional terms

• intrinsic factor; gastric intrinsic factor; IF; INF (GIF, IFMH)
• methylmalonate; methylmalonic acid (MMA)
• methylmalonic aciduria type A protein, mitochondrial (MMAA)
• methylmalonyl Coenzyme A mutase; succinyl CoA mutase; methylmalonyl CoA isomerase (MUT, MCM)
• Schilling test
• transcobalamin
• vitamin B12 deficiency
• vitamin B12 in serum/plasma

Component of

• adenosylcobalamin/cobalamin

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5280326
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3034025
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3000868
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=2831