methylmalonate; methylmalonic acid (MMA)

Introduction

In man it is involved in the degradation of several amino acids, odd-chain fatty acids & cholesterol via propionyl-CoA to the tricarboxylic acid cycle. Metabolism of methylmalonate is dependent upon adenosylcobalamin (vitamin B12).

More general terms

• malonate; malonic acid

Additional terms

• malonyl-CoA-acyl carrier protein transacylase, mitochondrial; MCT; mitochondrial malonyltransferase; [acyl-carrier-protein] malonyltransferase (MCAT, MT)
• methylmalonate in serum
• methylmalonic acidemia/aciduria
• methylmalonyl Coenzyme A mutase; succinyl CoA mutase; methylmalonyl CoA isomerase (MUT, MCM)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=487
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5288137