prostaglandin I3

Introduction

Produced by cyclooxygenase-2 in vascular endothelium. PGI2 is a vasodilator & inhibits platelet aggregation.

More general terms

• prostaglandin I (prostacyclin, epoprostenol {Flolan})
• 5,8,11,14,17-eicosapentaenoic acid [C20:5w3]

Additional terms

• eicosapentaenoate cyclooxygenase cascade