lomefloxacin (Maxaquin)

Introduction

Tradename: Maxaquin.

Indications

• bacterial infections due to susceptible organisms
  • urinary tract infection (UTI)
  • mild lower respiratory tract infection caused by:
    • Haemophilus influenzae
    • Moraxella catarrhalis
    • NOT Streptococcus pneumoniae
• prophylaxis for perioperative infection
  • prostate biopsy
  • genitourinary surgery

Dosage

400 PO BID

Tabs: 400 mg.

Antimicrobial activity

Gram positive

• Staphylococcus aureus (MSSA)
• Staphylococcus epidermidis

Gram negative

• Neisseria gonorrhoeae
• Moraxella catarrhalis
• Haemophilus influenzae
• Escherichia coli
• Klebsiella species
• Enterobacter species
• Serratia species
• Proteus mirabilis
• Proteus vulgaris
• Providencia species
• Morganella species
• Citrobacter species
• Aeromonas species
• Pseudomonas aeruginosa (+/-)
• Yersinia enterocolitica

Atypical bacteria

• Chlamydia species

More general terms

• fluoroquinolone

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3948
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=60622
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=68624