methyprylon (Noludar)

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Introduction

Tradename: Noludar. DEA-controlled substance: class 3.

Dosage

200-400 mg PO QHS

Tabs: 200 & 300 mg.

Pharmacokinetics

  • metabolized in liver to multiple products, some with pharmacologic activity
  • t1/2 of 4 hours, prolonged to 50 hours with acute overdose

elimination via liver

1/2life = 4 hours

elimination by hemodialysis = -

elimination by hemoperfusion = +

elimination by peritoneal dialysis = +/-

Adverse effects

Laboratory

More general terms

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Clinical Guide to Laboratory Tests, NW Tietz (ed) 3rd ed, WB Saunders, Philadelpha 1995

Database