dirithromycin (Dynabac)

Introduction

Tradename: Dynabac.

Indications

• bacterial infections due to susceptible organisms
  • pharyngitis, tonsillitis
  • bronchitis, pneumonia
  • skin or soft tissue infection

Dosage

500 mg PO QD for 7-14 days

Tabs: 250 mg.

Antimicrobial activity

Gram positive

• Streptococcus
  • Streptococcus group A
  • Streptococcus group B
  • Streptococcus group C
  • Streptococcus group G
• Streptococcus pneumonia
• Staphylococcus aureus (MSSA) (+/-)
• Staphylococcus epidermidis (+/-)

Gram negative

• Neisseria gonorrhoeae
• Moraxella catarrhalis
• Haemophilus influenzae (+/-)
• Legionella pneumophila

Atypical bacteria

• Chlamydia species
• Mycoplasma pneumonia

Anaerobes

• Clostridium species (+/-)

More general terms

• macrolide (macrolide antibiotic)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3034058
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3000507