dichloralphenazone (Kloralfenazon)

Introduction

DEA-controlled substance: class 4.

Indications

• used in combination preparations for treatment of vascular & tension headaches

Contraindications

• porphyria

Adverse effects

• drug rash

• drug adverse effects of psychotropic agents
• drug adverse effects of sedatives

Mechanism of action

• mild sedative
• dissociates on administration to form chloral hydrate & phenazone

More general terms

• sedative/hypnotic (tranquilizer)

Additional terms

• chloral [hydrate] (Noctec)

Component of

• acetaminophen/dichloralphenazone
• acetaminophen/dichloralphenazone/isometheptene (Midrin, Isocom, Amidrine)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=10188