arachidonate lipoxygenase cascade
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Biochemistry
- AA LPO cascade 1
- enzyme: 5-lipoxygenase
- substrate: arachidonate + O2
- product: 5-HPETE)
- AA LPO cascade 2
- enzyme: 12-lipoxygenase
- substrate: arachidonate + O2
- product: 12-HPETE
- AA LPO cascade 3
- enzyme: 15-lipoxygenase
- substrate: arachidonate + O2
- product: 15-HPETE
- AA LPO cascade 4
- AA LPO cascade 5
- AA LPO cascade 6
- AA LPO cascade 7
- enzyme: LTA synthase
- substrate: 5-HPETE
- product: LTA4
- AA LPO cascade 8
- enzyme: Leukotriene A4 hydrolase
- substrate: LTA4
- product: LTB4
- AA LPO cascade 9
- AA LPO cascade 10
- AA LPO cascade 11
- AA LPO cascade 12