PPXXF motif

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Introduction

Consensus motif in proline-rich region of Shank, metabotropic glutamate receptor-1 & the IP3 receptor. It serves as a binding site for the EVH1 domain of homer.

More general terms

References

  1. Sheng M. Molecular organization of the postsynaptic specialization. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7058-61. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11416187