allosteric site

Introduction

A site for non competitive binding of nonsubstrate different from the active site. Binding at the allosteric site brings about a conformational change of the enzyme, thus influencing its activity.

More general terms

• binding site
• peptide motif

More specific terms

• calmodulin binding site
• cyclic nucleotide-binding site
• cysteine switch
• phosphotyrosine interaction domain (PID, phosphotyrosine binding (PTB) domain, tyrosine kinase-binding (TKB) domain)
• src homology 2 [SH2] domain