Wilms tumor gene, WAGR gene or wt1

Introduction

Gene spans approximately 50 kilobases & contains 10 exons. 24 variants by alternative splicing, RNA editing & alternative. start sites. 3 distinct transcripts identified associated with 1 CpG island. WAGR gene (Wilm's tumor/aniridia/genito-urinary anomaly/mental retardation.

More general terms

• tumor suppressor gene or anti-oncogene

Database

• OMIM: https://mirror.omim.org/entry/194070
• OMIM: https://mirror.omim.org/entry/194080