ATP-binding cassette 1 (ABC1) gene
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Introduction
Loss of function mutations results in Tangier's disease. Transcription regulated by LXR-alpha & LXR-beta
More general terms
Additional terms
- LX nuclear receptor (LXR, oxysterol receptor)
- Tangier disease; high density lipoprotein (HDL) deficiency type 1; analphalipoproteinemia (HDLD1)
References
- ↑ Laffitte BA, Repa JJ, Joseph SB, Wilpitz DC, Kast HR, Mangelsdorf DJ, Tontonoz P. LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):507-12. Epub 2001 Jan 9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11149950