persephin; PSP (PSPN)

Function

• neurotrophic activity on mesencephalic dopaminergic neurons & motor neurons
• homodimer; disulfide-linked (putative)

Structure

• belongs to the TGF-beta family, GDNF subfamily

Compartment

secreted

More general terms

• TGF-beta family protein
• growth factor
• secreted protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5623
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5623
• OMIM: https://mirror.omim.org/entry/602921
• UniProt: http://www.uniprot.org/uniprot/O60542.html