CENPA-CAD (nucleosome distal) complex

Function

• interacts with the CENPA-NAC complex
• recruited to centromeres
• assembly of kinetochore proteins
• mitotic progression & chromosome segregation
• incorporation of newly synthesized CENPA into centromeres

Structure

• consists of:
  • CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR, CENPS

More general terms

• molecular complex