sec7 domain

Introduction

A common region of roughly 200 amino acids found in guanine nucleotide exchange factors (GNRP) specific for ADP-rybosylation factors (ARF). The SEC7 domains mediate interaction with ARF & catalyses GDP to GTP exchange

More general terms

• active site

Additional terms

• cytohesin ADP Ribosylation Factor (ARF) nucleotide binding site opener (ARNO)