regenerating islet-derived protein 3 alpha; reg III-alpha; pancreatitis-associated protein 1 (REG3A, HIP, PAP, PAP1)

Function

• might be a stress protein involved in the control of bacterial proliferation

Structure

contains 1 C-type lectin domain

Compartment

• secreted
• found in the apical region of pancreatic acinar cells

Expression

• constitutively expressed in intestine
• low expression is found in healthy pancreas
• appears in pancreatic juice after induction of pancreatic inflammation

Pathology

• overexpressed during acute pancreatitis & in some patients with chronic pancreatitis

More general terms

• lectin

Database

• UniProt: http://www.uniprot.org/uniprot/Q06141.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5068
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5068
• OMIM: https://mirror.omim.org/entry/167805