zinc finger protein ubi-d4; apoptosis response zinc finger protein; BRG1-associated factor 45D; BAF45D; D4, Zn+2 & double PHD fingers family 2; protein requiem (DPF2, BAF45D, REQ, UBID4)

Function

• may be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells
• might also have a role in the development & maturation of lymphoid cells

Structure

• belongs to the requiem/DPF family
• contains 1 C2H2-type Zn+2 finger
• contains 2 PHD-type Zn+2 fingers

Compartment

• nucleus, cytoplasm
• 30% nuclear, 70% cytoplasmic

Expression

ubiquitous

More general terms

• C2H2 type zinc finger protein
• pro apoptotic protein
• nuclear protein
• phosphoprotein

Additional terms

• apoptosis

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5977
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5977
• OMIM: https://mirror.omim.org/entry/601671
• UniProt: http://www.uniprot.org/uniprot/Q92785.html