cell death regulator Aven (AVEN)

Function

• protects against apoptosis mediated by Apaf-1
• binds Apaf-1, BCL-2 & BAD (Bcl-xl)

Compartment

• endomembrane system, peripheral membrane
• associated with intracellular membranes

Expression

• highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney & pancreas

More general terms

• pro apoptotic protein
• phosphoprotein

Additional terms

• apoptosis

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57099
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57099
• OMIM: https://mirror.omim.org/entry/605265
• UniProt: http://www.uniprot.org/uniprot/Q9NQS1.html