phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma (PIK3C2G)

Function

• phosphorylates PtdIns & PtdIns4P with a preference for PtdIns.
• does not phosphorylate PtdIns(4,5)P2

Structure

• belongs to the PI3/PI4-kinase family
• contains 1 C2 domain
• contains 1 PI3K/PI4K domain
• contains 1 PX (phox homology) domain

Compartment

peripheral membrane

Expression

• highly expressed in liver, prostate & testis
• lower levels in small intestine, kidney & pancreas

More general terms

• phosphatidylinositol-4-phosphate 3-kinase

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5288
• UniProt: http://www.uniprot.org/uniprot/O75747.html