complement C1s

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Introduction

activated by C1r to form C1s(dimer)

Function

Kinetic parameters:

Structure

Pathology

More general terms

Additional terms

Component of

References

  1. Baron M, Norman DG, Campbell ID. Protein modules. Trends Biochem Sci. 1991 Jan;16(1):13-7. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2053133
  2. Clinical Diagnosis & Management by Laboratory Methods, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1991, pg 832
  3. UniProt http://www.uniprot.org/uniprot/P09871.html
  4. C1Sbase; Note: C1S mutation db http://bioinf.uta.fi/C1Sbase/
  5. 5.0 5.1 5.2 5.3 5.4 Rossi V, Cseh S, Bally I, Thielens NM, Jensenius JC, Arlaud GJ. Substrate specificities of recombinant mannan-binding lectin- associated serine proteases-1 and -2. J Biol Chem. 2001 Nov 2;276(44):40880-7. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11527969
  6. 6.0 6.1 Hess D, Schaller J, Rickli EE. Identification of the disulfide bonds of human complement C1s. Biochemistry. 1991 Mar 19;30(11):2827-33. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2007122
  7. 7.0 7.1 Dragon-Durey MA, Quartier P, Fremeaux-Bacchi V et al Molecular basis of a selective C1s deficiency associated with early onset multiple autoimmune diseases. J Immunol. 2001 Jun 15;166(12):7612-6. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11390518

Database