complement C1 inhibitor; C1 esterase inhibitor (SERPING1, Cinryze, Berinert)

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Function

Structure

35% carbohydrate

Pathology

Pharmacology

  • C1 inhibitor (human from plasma); Tradenames: Cinryze, Berinert

Indications

Laboratory

  • see ARUP consult[2] Manufacturers: Lev Pharm (Cinryze), CSL Behring (Berinert)

Notes

More general terms

More specific terms

Additional terms

References

  1. OMIM https://mirror.omim.org/entry/106100
  2. 2.0 2.1 ARUP Consult: Hereditary Angioedema - C1-INH Deficiency The Physician's Guide to Laboratory Test Selection & Interpretation https://www.arupconsult.com/content/hereditary-angioedema
  3. ARUP Consult: C1-INH Deficiency Testing Algorithm The Physician's Guide to Laboratory Test Selection & Interpretation https://arupconsult.com/algorithm/c1-inh-deficiency-testing-algorithm
  4. 4.0 4.1 Longhurst H, Cicardi M, Craig T et al. Prevention of hereditary angioedema attacks with a subcutaneous C1 inhibitor. N Engl J Med 2017 Mar 23; 376:1131 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28328347 <Internet> http://www.jwatch.org/na43697/2017/03/23/new-preventive-treatment-hereditary-angioedema

Database