GRB2-associated-binding protein 3 (growth factor receptor bound protein 2-associated protein 3, GRB2-associated binder 3, GAB3)

Function

• unknown function
• interacts with PIK3R/p85, SHP2 & GRAP2/MONA
• may interact with Grb2
• phosphorylated on Tyr after macrophage colony-stimulating factor receptor (M-CSFR) stimulation

Structure

• belongs to the GAB family
• contains 1 PH domain

More general terms

• receptor
• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1397
• OMIM: https://mirror.omim.org/entry/300482
• UniProt: http://www.uniprot.org/uniprot/Q8WWW8.html