POU domain, class 5, transcription factor 1-like protein 3 (POU5FLC1, POU5F1P3, OTF3L, POU5F1L, POU5FLC12)

Structure

• belongs to the POU transcription factor family, class-5 subfamily
• contains 1 homeobox DNA-binding domain
• contains 1 POU-specific domain

Compartment

nucleus

Notes

• could be the product of a pseudogene
• several pseudogenes of POU5F1 have been described on chromosomes 1, 3, 8, 10 & 12
• 2 of them were shown to be transcribed in cancer tissues but not in normal ones, & may be involved in the regulation of POU5F1 gene activity in carcinogenesis

More general terms

• POU protein
• transcription factor (TF)

Additional terms

• POU domain, class 5, transcription factor 1-like protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9BZW0.html
• UniProt: http://www.uniprot.org/uniprot/Q9BZV8.html