TCP1 ring complex (T-complex protein 1, chaperonin containing T-complex polypeptide 1)
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Function
- molecular chaperone
- assists the folding of proteins upon ATP hydrolysis
- folding of actin & tubulin
- hetero-oligomeric complex of 850-900 kD that forms 2 stacked rings, 12-16 nm in diameter
- interacts with PACRG
Structure
Compartment
More general terms
References
- ↑ Yaffe MB, Farr GW, Miklos D, Horwich AL, Sternlicht ML, Sternlicht H. TCP1 complex is a molecular chaperone in tubulin biogenesis. Nature. 1992 Jul 16;358(6383):245-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1630491
- ↑ Lewis VA, Hynes GM, Zheng D, Saibil H, Willison K. T-complex polypeptide-1 is a subunit of a heteromeric particle in the eukaryotic cytosol. Nature. 1992 Jul 16;358(6383):249-52. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1630492
- ↑ UniProt http://www.uniprot.org/uniprot/O95149.html