natural killer cells antigen CD94; NK cell receptor; Killer cell lectin-like receptor subfamily D member 1; KP43; CD94 (KLRD1, CD94)

Function

• plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells & some cytotoxic T-cells
• can form disulfide-bonded heterodimer with NKG2 family members

Structure

contains 1 C-type lectin domain

Compartment

membrane

Alternative splicing

named isoforms=3

Expression

• natural killer cells

gamma/delta T cells

alpha/beta T cells

More general terms

• CD antigen
• killer cell lectin like receptor
• C-type lectin superfamily

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3824
• OMIM: https://mirror.omim.org/entry/602894
• UniProt: http://www.uniprot.org/uniprot/Q13241.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3824